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Occupational and Environmental Medicine

● BMJ

Preprints posted in the last 90 days, ranked by how well they match Occupational and Environmental Medicine's content profile, based on 18 papers previously published here. The average preprint has a 0.01% match score for this journal, so anything above that is already an above-average fit.

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Occupational burnout in the UK film and television industry: A cross-sectional survey of mental health, job quality, perceived stigma, and sexual harassment

Caldwell, M. S.; Chamberlain, R.; Rippon, D.

2026-10-20 occupational and environmental health 10.64898/2026.10.15.26365611 medRxiv
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Recent industry surveys have reported widespread concern about mental health, working conditions, and harassment in the UK film and television industry, but no peer-reviewed empirical study has examined the determinants of occupational burnout in this workforce. The present study tested whether physical health, mental wellbeing, perceived public stigma, intrinsic job quality, and sexual harassment exposure predict burnout in industry professionals. A cross-sectional online survey was completed by 415 individuals across more than 100 job titles, with 286 also completing an optional harassment module. Mental wellbeing sat well below population norms, with 68% scoring in the range indicative of probable depressive symptoms and 82% in the high-exhaustion range on the Maslach Burnout Inventory General Survey. Mental wellbeing and intrinsic job quality were the strongest predictors of burnout (R2 = .56), with meaningfulness accounting for most of the job-quality effect. Working hours independently predicted emotional exhaustion. Harassment exposure was associated with burnout in women but not men, approximately 30% mediated by mental wellbeing; sexist behaviour directly predicted exhaustion in women. Workers with a disability reported higher stigma. Burnout was strongly associated with intent to leave, and the findings collectively indicate an industry-wide occupational health concern requiring structural rather than individual-level intervention.

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Lived experiences and occupational pressures among Vietnamese nail salon workers in Maryland

Nguyen, K. K.; Agree, E. M.

2026-09-11 occupational and environmental health 10.64898/2026.09.10.26362742 medRxiv
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Individuals of Vietnamese descent comprise a majority of the United States nail salon workforce. Whereas prior research has centered on chemical exposures, thematic analysis of interviews with Vietnamese nail salon workers around Baltimore, Maryland examined the lived experiences of nail salon workers. Six themes were identified: (1) nail work as a familial livelihood and a sacrifice-oriented pathway towards intergenerational mobility; (2) perceived flexibility within the workplace with low control; (3) professional pride grounded in artistry, detail, and customer care; (4) cumulative occupational risks; (5) emotional labor as an expected and core component of nail salon work; and (6) limited perceived capacity to change working conditions. These findings suggest that the occupational pressures in nail salon work cannot be solely framed as a lack of worker knowledge or motivation towards adopting safer practices. Intervention success depends on a holistic view of workers' lives, whose choices are shaped by family obligations, customer demands, and conditions largely outside their control. Therefore, efforts to improve nail salon health may benefit from shifting the burden of risk management away from individual workers and engaging the wider community.

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Occupational Physical Activity Paradox and Incident Cardiovascular Disease: Does Exposure Classification Matter?

Okoro, W. O.; Demou, E.; Celis-Morales, C. A.; Ryde, G. C.

2026-07-27 occupational and environmental health 10.64898/2026.07.23.26358767 medRxiv
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Objectives The association between occupational physical activity (OPA) and cardiovascular disease (CVD) may depend on how OPA is classified. This study examined the association between OPA and incident CVD using individual level and occupational group level classifications, and assessed whether factors contributing to attenuation differed. Methods A total of 137,592 employed UK Biobank participants aged 40 to 69 years who were free of CVD at baseline were included. OPA was classified using (i) individual level self reported physical activity at work and (ii) occupational group level two digit Standard Occupational Classification. Associations with incident CVD were examined using Cox proportional hazards models. Attenuation of associations by sociodemographic, lifestyle, health, occupational and psychosocial factors was assessed using univariate adjustments and Heller's coefficient. Results During 1,656,378 person-years of follow up (median 12.6 years), 10,465 incident CVD events occurred. The association between OPA and CVD differed markedly according to exposure classification. High individual level self reported OPA was associated with increased CVD incidence after full adjustment [hazard ratio (HR) 1.19, 95% confidence interval (CI) 1.10 to 1.27]. In contrast, no association was observed when OPA was classified at the occupational-group level using Standard Occupational Classification groupings (HR 1.00, 95% CI 0.94 to 1.06). Sociodemographic and health factors accounted for the greatest attenuation across both classifications, whereas psychosocial factors contributed primarily to associations based on individual-level self-reported OPA. Conclusions The association between occupational physical activity and incident cardiovascular disease differed substantially according to how OPA was classified. These findings highlight exposure classification as a critical consideration when interpreting evidence on the physical activity paradox.

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Protecting the protectors: Occupational burden and management of work-related musculoskeletal disorders among Cameroonian healthcare professionals and the Sustainable Development Goals

Kum, M. B.; Meh, B. K.; Buh, F. C.; Mandengue, S. H.; Bopda, O. S. M.

2026-08-02 occupational and environmental health 10.64898/2026.07.30.26359338 medRxiv
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Work-related musculoskeletal disorders (WRMSDs) constitute the primary occupational health burden among healthcare professionals (HCPs) globally and directly threaten health workforce sustainability, a critical concern for Sustainable Development Goal 3 (Good Health and Well-being) and SDG 8 (Decent Work and Economic Growth). Despite high prevalence in Cameroon, downstream occupational effects and management strategies across hospital levels remain undocumented. A hospital-based, analytical cross-sectional study was conducted across five referral hospitals in Douala, Cameroon (2019-2022). A total of 561 HCPs were enrolled by stratified random sampling. The Modified Nordic Musculoskeletal Questionnaire and structured interviews assessed WRMSD occupational effects and management strategies. Data were analysed using IBM SPSS v26; chi-square tests and logistic regression assessed associations (p < 0.05). The 12-month WRMSD prevalence was 83.4% (468/561). WRMSDs caused absenteeism in 83.4% of affected HCPs ({chi}2 = 14.414; p < 0.001), reduced daily activity capacity in 55.6%, and job dissatisfaction in 60.4%; 38.9% were considering a career change. Management was predominantly reactive: fitness training (76.3%), rest (41.4%), and non-steroidal anti-inflammatory drugs (NSAIDs; 37.3%). Only 15.0% received physiotherapy referral, and no hospital had a formal WRMSD protocol. WRMSDs impose a substantial and measurable occupational burden on HCPs in Douala. Current management is reactive, non-standardised, and under-integrated with physiotherapy. Evidence-based, multicomponent prevention programmes, physiotherapy integration, and a national occupational health policy are urgently required to protect the healthcare workforce and advance SDG 3 and SDG 8 targets in Cameroon.

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Chronotype distinctness a key risk factor for emotional and cognitive disruption in shift working nurses

Davies, A.; Hickman, R.; Cai, Z.; Lai, D. J.; Hampshire, A.; Hellyer, P. J.; Shergill, S.; D'Oliveira, T.

2026-08-24 occupational and environmental health 10.64898/2026.08.21.26361010 medRxiv
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The prevalence of shift work-centric industries and the rise of flexible working render it crucial to investigate the health risks posed by unnatural patterns of work and sleep. Shift working in healthcare has been linked to emotional dysregulation, reduced alertness, and cognitive impacts, with Shift Work Disorder (SWD) classified as a circadian rhythm sleep-wake disorder in the DSM-5. These impacts have historically been attributed to schedule-related sleep disturbances; however certain individuals appear more acutely affected. One measure of individual inflexibility to altered routines is chronotype distinctness, an amplitude dimension of the Caen Chronotype Questionnaire (CCQ). Here, we use Structural Equation Modelling (SEM) to unravel the mechanisms by which sleep and chronotype distinctness govern the neuropsychiatric symptom profiles of a cohort of National Health Service (NHS) shift workers (n=102). We constructed a measurement model, extracting latent constructs from questionnaires for sleep disturbances (PSQI), chronotype distinctness (CCQ), mood disorder (MDQ), depression (PHQ8) and emotional reactivity (ERS), and cognitive assessments. Correlations were identified between constructs, then translated into two SEMs - day and rotating shifts respectively - with sleep and distinctness as predictors of detrimental effects. Models were tested for direct effects, significant paths, and overall model fit. We found that, whilst sleep governed fatigue-based symptoms in day-shift workers, chronotype distinctness determined the severity of adverse effects in rotating-shift workers, including mood disorders and cognitive impairments. We surmise that high chronotype distinctness should be considered a risk factor for adverse effects surrounding night and rotating-shift work, and that interventions should incorporate chronotype-specific remediation.

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Work-related Musculoskeletal Pain Among Factory Workers in Kigali: Prevalence and Coping Strategies

Dusabeyezu, P.; Sagahutu, J. B.; Kemigisha, J.

2026-08-25 occupational and environmental health 10.64898/2026.08.22.26361118 medRxiv
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Background: Work-related musculoskeletal pain (MSP) is a prevalent concern among factory workers, impacting productivity, absenteeism, and overall quality of life. Factory workers, who perform repetitive tasks and engage in physically demanding work, are particularly susceptible to work-related MSP. Methods: This descriptive cross-sectional quantitative study included 148 factory workers (29 females and 119 males) from two factories in Kigali, surveyed between November 2023 and January 2024. Data were collected using a structured questionnaire that included demographic items, the Modified Nordic Musculoskeletal Questionnaire (M-NMQ) to assess work-related musculoskeletal pain (MSP) symptoms in nine body regions over the previous 12 months and seven days, and questions regarding interference of symptoms with normal work activities. The Coping Strategies Questionnaire (CSQ) was administered to identify coping practices among factory workers. Data analysis comprised descriptive statistics, including mean, frequency, Wilson 95% confidence intervals, and percentage values, calculated using SPSS version 25.0. Results: Participants were predominantly male (119/148, 80.4%), and 98/148 (66.2%) had worked at the factory for more than five years. Overall, 113/148 reported symptoms in at least one body region during the previous 12 months (76.4%, 95% CI 68.9-82.5). The lower back (90/148, 60.8%), shoulders (71/148, 48.0%), neck (61/148, 41.2%), and knees (58/148, 39.2%) were most frequently affected. Symptoms prevented normal work for 41/148 (27.7%, 95% CI 21.1-35.4), and 57/148 reported symptoms during the previous seven days (38.5%, 95% CI 31.1-46.5). Among 113 participants with 12-month symptoms, the most frequent Always responses were seeking medical help (78/113, 69.0%), rest and recovery (75/113, 66.4%), and medication use (59/113, 52.2%); ergonomic adjustment was least frequent (10/113, 8.8%). Conclusion: Self-reported work-related MSP symptoms were common, particularly in the lower back and shoulder, while ergonomic adjustments were uncommon. Frequent medication use highlights the need for comprehensive interventions combining ergonomic training, physiotherapy, and adequate recovery; however, these findings do not establish causation or intervention effectiveness.

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Emergency Department Length of Stay, Employment Status, and Subsequent Risk of Hospitalisation: A survival analysis of linked administrative records in England

Aston, H.; Nafilyan, V.; Boyle, A.; Ayoubkhani, D.

2026-10-07 health economics 10.64898/2026.10.05.26364765 medRxiv
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Objectives To investigate the association between time spent in NHS Type 1 emergency departments (EDs, consultant led 24 hour services with full resuscitation facilities) and risk of leaving employment and hospitalisation after leaving the department alive up to two years after attendance. Methods We conducted a retrospective cohort study using linked administrative data from the NHS Emergency Care Dataset, Hospital Episode Statistics, Census 2021, and mortality records. ED length of stay was categorised from under 2 hours to 12 hours or more. Cox proportional hazards models were fitted to estimate the association between ED length of stay and subsequently leaving employment or being hospitalised over a two year follow-up period, adjusting for demographic, socioeconomic, and clinical characteristics. Results Our study population comprised 3,347,008 individuals aged 25 to 64 who attended a Type 1 ED in England between April 2021 and March 2023. For leaving employment, adjusted hazard ratios (aHRs) increased from 1.04 (95% CI 1.03 to 1.06) for stays of 2 to <4 hours to 1.21 (1.17 to 1.24) for 12 hours or more, compared with stays under 2 hours. A similar but more pronounced gradient was observed for post-discharge hospitalisation, with aHRs rising from 1.06 (1.04 to 1.07) at 2 to <4 hours to 1.95 (1.91 to 1.99) for stays of 12 hours or more. Conclusions Prolonged time spent in the ED is associated with poorer outcomes among working-age employees, including reduced labour market participation and increased hospital use. These findings suggest that long ED stays may have wider and longer-term implications beyond immediate clinical outcomes, including potentially for national labour markets and economic growth.

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Knowledge, attitudes, and practices related to ocular safety among maintenance workers in a Ghanaian university: A cross-sectional study

Kwarteng, C.; Brew, F. M.; Owusu, E.

2026-09-03 occupational and environmental health 10.64898/2026.09.01.26361906 medRxiv
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Occupational ocular injuries are a preventable yet neglected public health problem, particularly in low- and middle-income countries. Maintenance workers are exposed to diverse ocular hazards daily, yet compliance with protective measures is consistently poor. A descriptive cross-sectional study was conducted among 85 maintenance workers at the Maintenance and Essential Services Organization (MESO) of Kwame Nkrumah University of Science and Technology (KNUST), Ghana, recruited through stratified convenience sampling across seven occupational sections. A structured questionnaire assessed knowledge of ocular hazards and protective equipment, attitudes toward ocular safety, and safety practices. Data were analyzed using IBM SPSS version 26 (IBM Corp., Armonk, NY, USA); chi-square and Fishers exact tests assessed associations (p < 0.05). Participants were predominantly male (84/85, 98.8%), with a mean age of 44.5 {+/-} 10.4 years. Overall knowledge was good (mean 9.40 {+/-} 1.59 out of 11), but attitude and practice scores were average (2.78 {+/-} 0.92 and 3.27 {+/-} 0.93, respectively). Most workers correctly identified goggles and face shields as protective, but only about half recognized that ordinary sunglasses and spectacles offer inadequate protection. Although 97.6% (83/85) recognized the need for ocular protection, only 7.1% (6/85) reported consistent protective eyewear use, and fewer than half (45.9%, 39/85) had received formal ocular safety training. Routine general protective equipment use was significantly associated with ocular protection use (Fishers exact test, p = 0.011). Sand and dust particles were the leading causes of injury and only 25% (5/20) of injured workers sought formal care. Workers demonstrated good knowledge but poor attitudes and practices toward ocular safety, suggesting that knowledge alone does not translate into protective behaviour even within a relatively well-resourced institutional setting. Findings suggest that limited access to task-appropriate protective eyewear may represent an important institutional barrier. Institutional PPE supply and section-specific safety training are essential to bridge this knowledge-practice gap.

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MAPEVAScR: a four-phase framework integrating transparent rule based text mining, evidence gap mapping and a mandatory human validation gate for scoping reviews framework development and empirical validation in occupational health.

ERAS LEVANO, C. J.

2026-09-10 occupational and environmental health 10.64898/2026.09.08.26362521 medRxiv
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Background. Automation is increasingly used to reduce the screening workload of evidence syntheses, but its error is real, variable and rarely reported. The 2025 joint position statement of Cochrane, Campbell, JBI and the Collaboration for Environmental Evidence mandates human oversight of artificial intelligence in evidence synthesis, yet, as of today, no international guideline requires quantitative measurement and reporting of automated-screening error against a human gold standard. Methods. We developed MAPEVAScR (MAPeo de EVidencia con VAlidacion humana), a four phase framework for scoping reviews: (A) datalake construction with deterministic, traceable deduplication; (B) transparent, record level auditable rule based text mining with confidence tiers; (C) evidence gap mapping that feeds back human screening prioritisation; and (D) a mandatory human validation gate verifying 100% of the candidate corpus and issuing a quantitative screening error report (per tier precision, confusion matrix, falsepositive families, documented changes to conclusions). The framework was empirically validated on a scoping review of epilepsy and occupational fitness (2015 to 2025; PubMed, Scopus, Web of Science): a funnel of 2,008 [-&gt;] 1,435 [-&gt;] 1,114 [-&gt;] 230 records was reduced to 127 human confirmed inclusions (present study). Results. The rule based filter achieved a global precision of 55.2% (Tier A 75.5%, Tier B 37.5%, Tier C 45.8%); human validation identified 103 false positives classifiable into seven reproducible error families, and 107 of 127 included records required human correction of automated thematic labels. Without the gate, the review's central thematic conclusion would have been published reversed: automated labelling ranked Aptitude/employability third (12.6% of records), whereas after validation it ranked first (73.2%) (present study). Conclusions. A mandatory human validation gate with quantitative error metrics closes a reporting gap that current guidelines leave open: in the present study it prevented publication of an inverted synthesis. We propose the screening error report as a minimum reporting standard for any evidence synthesis using automated screening. Keywords: scoping review; text mining; human validation; automation bias; evidence gap map; occupational health; epilepsy; PRISMAScR

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Assessing hospital workers' health: a tool for longitudinal health monitoring in a public tertiary hospital in Brazil's Unified Health System (SUS)

Amancio, R. T.; Cruz, L. N.; Dantas, R. d. S.; Gomes, M. P.; Silva, A. d. A. B. d.; Brasil, P. E.

2026-08-31 occupational and environmental health 10.64898/2026.08.27.26361318 medRxiv
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Background: Health and administrative professionals in tertiary hospitals face high levels of occupational stress, mental illness, and multimorbidity. The integrated measurement of these multidimensional health aspects is essential for informing effective workplace health promotion strategies. Objective: To describe the general health status of federal public hospital staff and correlate the measured health dimensions to inform institutional health promotion initiatives. Methods: A cross-sectional, online survey study was conducted at Hospital Universitario dos Servidores do Estado (HUSE) between November and December 2025. Data collection was performed via online REDCap questionnaires covering sociodemographic profiles and validated instruments (SRQ-20, MIDAS, AUDIT, WHOQOL-BREF, PHI, WHOQOL-SRPB BREF, CBI, GPAQ, and EPSO). Descriptive statistics, comparisons across employment ties (permanent vs. contracted staff), and Spearman correlation matrices were calculated. Results: Among 197 accesses, 117 completed the informed consent, and 86 finished all questionnaires. Participants were predominantly female, aged 40 to 60 years, and Christian. Screening positivity was 25% for common mental disorders, 21% for headache-related disability, and 10% for harmful drinking. Burnout scores clustered in the second quartile, while quality of life, happiness, and spirituality scores were in the upper third. Median physical activity was 670 min/week. Mental symptoms (SRQ-20), headache (MIDAS), and burnout (CBI) correlated positively with each other and negatively with quality of life, happiness, spirituality, and institutional support (EPSO). Conclusion: The set of instruments proved feasible for situational health diagnosis among hospital staff. Although the sample size was limited in this baseline wave, the initiative fostered workplace health awareness, driving concrete initiatives, including an on-site functional gym and workplace vaccination campaigns.

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Sociodemographic and occupational factors associated with general sick leave among public school teachers in Bogota: A retrospective cohort study, 2010-2025

Bayona-Rodriguez, H.; Sanchez-Santiesteban, D.; Buitrago, G.

2026-08-10 occupational and environmental health 10.64898/2026.08.06.26359845 medRxiv
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Background: General illness-related sick leave among teachers represents a relevant public health and workforce management issue. However, long-term population-based evidence describing its distribution and associated factors in Latin American urban educational systems remains limited. This study aimed to characterize the occurrence, distribution, duration, and sociodemographic, occupational, temporal, and territorial factors associated with general illness-related sick leave among public school teachers in Bogota between 2010 and 2025. Methods: A retrospective cohort study was conducted using integrated administrative databases from the Bogota District Department of Education. The primary outcome was the occurrence of at least one general illness-related sick leave episode in a teacher-month observation. Descriptive analyses were performed to characterize sociodemographic and occupational patterns. A multivariable logistic regression model was used to estimate associations. Month and year were included as temporal fixed effects to account for seasonal patterns, academic-calendar effects, pandemic-related disruption, and secular changes. Results: The cohort included 59,697 unique teachers, contributing 537,025 teacher-year observations from teachers with an active employment record between January 1, 2010, and July 31, 2025. Overall, 41.59% of teacher-year observations included at least one general illness-related sick leave episode, and 83.26% of teachers had at least one episode at any time during follow-up. Respiratory diseases accounted for the largest share of episodes, followed by musculoskeletal and infectious diseases. Mean duration varied substantially by diagnostic category, ranging from short respiratory and infectious episodes to longer absences related to neoplasms, circulatory diseases, injuries, and mental health conditions. In the multivariable teacher-month model, sick leave occurrence was associated with age, sex, occupational role, teaching area, contract type, locality, calendar month, and calendar year. Lower odds were observed among male teachers, principals, and teachers with provisional contracts, while temporal and territorial variation was observed across months, years, and localities. Conclusions: General illness-related sick leave among public school teachers in Bogota showed consistent sociodemographic, occupational, temporal, and territorial patterns. Respiratory and musculoskeletal conditions accounted for the largest share of episodes, while chronic, neoplastic, injury-related, circulatory, and mental health conditions were associated with longer durations. These findings provide population-level evidence to inform occupational health surveillance, seasonal preparedness, and workforce planning strategies within urban educational systems.

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Internal Dose Benchmarking of Acrylamide Exposure and Peripheral Neuropathy Risk: A National Population-Based Validation Study

Hamed, K. J. A.; Bundid, R. M.; Sayah, M. A.; Gamal, M.; Taha, R. S. M.; Nuri, N.

2026-08-12 toxicology 10.64898/2026.08.10.26360101 medRxiv
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Abstract Background. Acrylamide, a neurotoxicant in heated foods and smoke, is linked to occupational neuropathy, but evidence regarding chronic, low-level population exposure remains limited. We evaluated the association between acrylamide exposure biomarkers and peripheral neuropathy among U.S. adults. Methods. A total of 2,266 NHANES 2003-2004 participants (age >40) were analyzed. Exposure was assessed via hemoglobin adducts (HbAA/HbGA); neuropathy via monofilament testing >1 site). Survey-weighted logistic regression models adjusted for confounders. Sensitivity analyses included cubic splines, diabetes stratification, and multiple imputation. Results. Neuropathy prevalence was 15.5%. In adjusted models, neither adduct was associated with neuropathy (HbAA OR: 0.98, 95% CI: 0.82-1.17; HbGA OR: 0.91, 95% CI: 0.77-1.08). No dose-response gradient was observed. Expected risk factors (age, diabetes) showed strong associations, validating model sensitivity. The null result remained robust across sensitivity analyses, including a stricter outcome definition and multiple imputation (pooled OR: 0.97, 95% CI: 0.83-1.14). Conclusions. Acrylamide adducts were not associated with peripheral neuropathy in this national sample. General population levels (~55-70 pmol/g) lie well below established occupational no-observed-adverse-effect levels (~510 pmol/g) and clinical neuropathy thresholds (~6,000 pmol/g), providing a mechanistically coherent explanation for this null result.

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Inhalation exposure to methamphetamine in contaminated residences

Dennison, J.

2026-10-13 occupational and environmental health 10.64898/2026.10.02.26364615 medRxiv
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Current health risk assessments from thirdhand exposure to methamphetamine (meth) to occupants of contaminated residences when no cooking or use is still occurring assume that inhalation exposure is insignificant. After Wright et al. (2021) reported substantial meth concentrations in a contaminated residence, the present study was conducted to further test the hypothesis that concentrations were high enough to contribute to total occupant dose. Air sampling was conducted in contaminated residences that had been previously sampled for surface contamination. Samples were collected on personal sampling pumps in fixed locations on treated glass fiber filters is cassettes and analyzed by gas or liquid chromatography with mass spectroscopy. Sixty-nine samples were collected from eighteen residences for the study. Meth concentrations ranged from 0.02 to 15 ug/m3. Concentrations in supply air vents were significantly higher than in return vents or in ambient air. Residences with no HVAC systems (baseboard heat) had airborne concentrations similar to residences with HVAC systems turned off, and lower than when HVAC was on. Whether a residence was occupied or not did not show differences. All data from residences with HVAC had a significant correlation with surface concentrations (R2 = 0.61) but some factors that affected results were not determined in the study. In the context of the risk assessment and regulatory standard established by California and adopted in several other states, the inhalation exposure would approximately double total occupant dose for infants, and this population would exceed the California reference dose by approximately 100%. Further studies should be conducted to refine these estimates and determine the factors that influence airborne concentrations.

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Success Among Ethnic Minorities and International Medical Graduates in UK Medical Speciality Recruitment: A Longitudinal Analysis of NHS England Data (2021-2025)

Hum, R. M.; Shafi, H. A.; Sharma, S. D.; Marshall, L. M.

2026-10-07 medical education 10.64898/2026.10.06.26364840 medRxiv
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Background While overall application volume by ethnic minority doctors into UK postgraduate medical training has expanded significantly, workforce diversity varies substantially across specialties. Previous reports have suggested that doctors from certain ethnic backgrounds and international medical graduates (IMGs) experience lower likelihoods of securing training posts, but granular longitudinal evaluations across all specialty training levels and recruitment stages remained limited. Therefore, this study evaluates longitudinal trends in self-reported ethnicity and country of qualification across postgraduate medical training in England between 2021 and 2025, maps specialty representation, and tests the hypothesis that recruitment success rates differ significantly between ethnic minority and White baseline applicants. Methods We conducted a retrospective national longitudinal analysis of mandatory NHS specialty recruitment data across England from 2021 to 2025, encompassing over 300,000 applications across ST1/CT1 (entry-level) and ST3+ (higher specialty) pathways. Applicants were categorised into census-aligned broad and granular ethnic groups, alongside IMG classifications. Unadjusted odds ratios (ORs) with 95% confidence intervals were calculated using White graduates and internal sub-ethnic baselines as comparators. Specialty-level ecological correlations (Spearman's rho) were performed to evaluate whether international workforce reliance moderated ethnic recruitment disparities. Results Between 2021 and 2025, applicant volume expanded rapidly, with ethnic minority applicants and IMGs comprising numerical majorities. However, Asian and Black applicants experienced substantially lower odds of receiving training offers compared to White baseline applicants across multiple high-volume specialties (e.g., emergency medicine and anaesthetics at ST1, where Black applicants faced multi-fold reductions in success odds: OR 0.03 to 0.05, p<0.001). Granular analyses revealed notable intra-ethnic heterogeneity, including lower success among Pakistani and Bangladeshi applicants compared to Indian applicants. Furthermore, UK graduates maintained higher offer success than IMGs across most specialties. Ecological correlations demonstrated that higher international applicant reliance was moderately and significantly associated with wider recruitment disparities at higher training levels for Black applicants {rho}=-0.43, p=0.019). Conclusions Centralised medical recruitment in England exhibits some persistent ethnic and international qualification disparities despite rising application diversity. The findings highlight the necessity of disaggregating ethnic groups and addressing subjective evaluation vulnerabilities within multi-stage recruitment processes to foster equity. Trial registration: Not applicable

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Staff perceptions of an NHS military veterans mental health service in the UK: A qualitative evaluation

Talwar, S.; Carlos Osorio, C.; Barslund Blackman, E.; Solomons, S.; Krishnamurthy, J.; Kuhn, R.; Culloty, L.; Greene, T.; Ferrier, S.; Billings, J.

2026-10-08 psychiatry and clinical psychology 10.64898/2026.10.06.26364875 medRxiv
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Those leaving military service frequently present with complex psychosocial problems, but military veterans are often reluctant to engage with statutory healthcare provision. Specialist mental health services have recently been established in the UK to specifically support military veterans with their psychological and social wellbeing. We explored the treatment and support provided by the London branch of a military veterans mental health and wellbeing service (Op COURAGE) from the perspectives of the multidisciplinary service team and their partner organisations and collaborators. We conducted semi-structured interviews with multidisciplinary service staff and members of their partner organisations and external agencies. Qualitative data were analysed using framework analysis.?A total of 16 professionals participated in this study, comprising five service staff, eight collaborators and three partner agency participants. Five themes with subthemes were identified, including (1) blended networks, (2) staff inclusivity and sensitivity, (3) spectrum of psychosocial interventions and holistic support, (4) referral mechanisms, and (5) (in)visibility of the service and advertising. Our evaluation highlighted the advantages of a multidisciplinary team and collaborative partnerships to meet the psychosocial needs of veteran and their significant others. We have proposed that service improvement could include increasing advertisement about this specialist service, deepening knowledge about veterans among staff and further involving veterans and key stakeholders in service decisions.

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Rotating Night Shift Work and Risk of Incident Cardiovascular Disease and Mortality by Chronotype: A Prospective Cohort Study in Nurses' Health Study II

Kianersi, S.; Liu, Y.; Sofer, T.; Agarwal, I.; Scheer, F. A. J. L.; Guasch-Ferre, M.; Redline, S.; Schernhammer, E.; Rexrode, K.; Huang, T.

2026-09-17 epidemiology 10.64898/2026.09.16.26363233 medRxiv
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Introduction: Rotating night shift work is associated with chronic circadian disruption and may contribute to higher cardiovascular disease (CVD) risk and mortality. The impact of rotating night shift work may vary by chronotype, particularly when an individual's circadian preference is misaligned with work schedules. Methods: In 2009, 69,458 women (mean age 54.4 years) free of CVD in the Nurses' Health Study II reported chronotype. Duration of rotating night shift work has been assessed biennially since 1989. Participants were followed from 2009 through June 2021 for incident CVD (myocardial infarction or stroke) and all-cause mortality. We used time-varying Cox proportional hazards models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for outcomes in relation to rotating night shift work and chronotype and to evaluate whether the associations differed by chronotype. Primary models adjusted for key demographics, CVD risk factors, and workplace factors. Results: We documented 1,005 incident CVD events over 800,630 person-years and 1,777 deaths over 806,043 person-years. Each 5-year increase in rotating night shift work was associated with a modestly higher risk of incident CVD (HR 1.07; 95% CI 1.01, 1.14) and a 13% higher risk of all-cause mortality (HR 1.13; 95% CI 1.08, 1.17). Greater eveningness was associated with higher incident CVD risk (HR 1.17; 95% CI 1.06, 1.28) and all-cause mortality (HR 1.18; 95% CI 1.10, 1.26). For incident CVD, the increased risk per 5-year increment in rotating night shift work was observed only among definite morning types (HR 1.11; 95% CI 0.99, 1.23), but not among definite evening types (HR 0.99; 95% CI 0.86, 1.15; p-interaction=0.1732). For all-cause mortality, the increased risk associated with shorter-term rotating night shift work (<5 years) was more evident among definite morning types (HR 1.39; 95% CI 1.12, 1.73) than definite evening types (HR 1.37; 95% CI 0.98, 1.91). However, this difference was not observed for longer duration of shift work ([&ge;]5 years), and the overall interaction was not statistically significant (p-interaction=0.57). Similar patterns were observed when shift work duration was modeled continuously using restricted cubic spline analyses. Conclusion: Rotating night shift work was associated with a modest increase in CVD and all-cause mortality risk. The overall pattern of associations across chronotypes suggested that nurses with a morning chronotype may be more susceptible to the adverse effects of rotating night shift work.

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Anticipatory nursing work and the co-construction of discharge readiness in coronary care units: A cross-national qualitative study

Rashidi, A.; Dunham, M.; KINLEY, E.; Bueser, T.; Glass, C.; Jones, I.; Makokha, M.; Whitehead, L.; Newson, L.

2026-08-05 nursing 10.64898/2026.08.03.26358968 medRxiv
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Abstract Background: Hospital discharge from coronary care units (CCUs) is commonly framed as a discrete clinical or administrative endpoint. This event-based conceptualisation obscures the ongoing nursing and interprofessional work undertaken across the admission to stabilise discharge readiness. Aim: To theorise discharge readiness in CCUs as anticipatory nursing and interprofessional work and to examine how professional roles, organisational systems and service contexts shape discharge across two national context. Design: Qualitative study utilising reflexive thematic analysis. Methods: Semi-structured interviews and focus groups were conducted with 37 clinicians (nurses, allied health professionals and medical staff) working in CCUs in Australia and the United Kingdom. Reflexive Thematic Analysis was undertaken inductively within each dataset, followed by higher-level interpretive integration. Results: Four interrelated themes conceptualised discharge readiness as: (1) anticipatory nursing work initiated at admission and sustained through ongoing assessment, coordination and documentation; (2) negotiated readiness achieved through interprofessional alignment and distributed expertise; (3) discharge documentation as a site of organisational tension shaping workflow and communication; and (4) discharge flow constrained by system-level pressures, downstream service availability and policy logics. Across both national contexts, nurses were positioned as custodians of discharge readiness through continuous monitoring, relational coordination and informal risk management, although enactment varied by organisational setting. Conclusion: This study contributes to nursing scholarship by positioning discharge readiness not as a single decision point, but as an emergent outcome of anticipatory nursing labour, interprofessional negotiation and organisational systems. By making visible the distributed and often hidden work underpinning discharge, the findings extend existing models of transitional care and provide a theoretically grounded foundation for strengthening discharge practice in coronary care nursing.

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Evaluating Nursing Performance During Heatwave Simulations: Protocol for a Repeated Measures Cross-Over Study

Blount, H.; Bingham, L.; Esteves, N. K.; Daniels, T.; Filingeri, V.; Aceves-Gonzalez, C.; Brooks, K.; Watts, N.; Jones, D.; Tewksbury, A.; Jenkins, K.; James, P.; Sach, T.; Nunes, A. R.; Roberts, T.; DallOra, C.; Portillo, M. C.; Maguire, C.; Raisbeck, L.; Costantini, T.; Clarkson, P.; West, P.; Street, N.; Gordon, R.; Worsley, P. R.; Filingeri, D.

2026-09-21 occupational and environmental health 10.64898/2026.09.18.26363404 medRxiv
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This study protocol combines clinical simulations with climatic chamber experiments, to evaluate 1) the impact of heat stress on hospital nurses physiological strain, physical and mental fatigue, vigilance, and clinical performance; and 2) the efficacy of a practical cooling intervention (i.e. electric fan) in mitigating the negative impact of heat stress. UK-based, registered adult nurses working in hospital settings will be recruited to partake in a repeated-measures cross-over design study, consisting of five separate 3-hour experimental sessions simulating clinical work, and taking place within a climatic chamber at Southampton General Hospital (UK). Sessions will differ by ambient temperature and cooling intervention as follows: 1) control (CTR; 18{degrees}C, 50% relative humidity [RH]); 2) warm (WARM; 26{degrees}C, 50%RH); 3) warm with electric fan (WARM+FAN; 26{degrees}C, 50%RH); 4) hot (HOT; 34{degrees}C, 50%RH); 5) hot with electric fan (HOT+FAN; 34{degrees}C, 50%RH). This study has been registered on a publicly accessible clinical trial registry (ISRCTN45793399). During each session, participants will first complete a standardised fatigue-induction protocol simulating shift work (i.e. low-intensity cycling with cognitive tasks); followed by a simulated hospital ward round involving six simulated patients and two simulated cardiac arrest scenarios. Nursing cognitive and physical performance will be assessed using a standardised observational assessment battery, along with objective cardiopulmonary resuscitation (CPR) performance metrics. Physiological responses will be assessed by monitoring changes in core temperature (Tcore), skin temperature (Tskin), heart rate, and whole-body sweat loss (WBSL). Fatigue and vigilance will be measured using the Swedish Occupational Fatigue Inventory (SOFI) and Brief Psychomotor Vigilance Task (PVT-B), respectively. Baseline (i.e. prior to fatiguing protocol) to post simulation changes in 1) vigilance assessed via the PVT-B (i.e. a determinant of role-specific cognitive performance); 2) CPR quality score (i.e. a determinant of role-specific physical performance); and 3) Tcore (i.e. a determinant of thermo-physiological state); will be analysed using linear mixed models to determine the effects of ambient temperature and cooling intervention on nurses clinical and physiological performance. By providing a controlled methodological framework for assessing the effects of heat exposure on hospital nurses physiological, perceptual, and clinical performance, this study will provide empirical evidence on air temperature-related changes in nursing performance and physiological strain and the role of cooling interventions in modifying these responses. This will support the development of evidence-based climate adaptation strategies to protect healthcare staff wellbeing and maintain patient safety during periods of extreme heat.

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Swiss physicians' experiences of sexual harassment at work. A nationwide survey

Dzi, K. T.; Jox, R.; Bodenmann, P.

2026-10-21 public and global health 10.64898/2026.10.19.26365908 medRxiv
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Background: Workplace discrimination and violence against health workers including sexual harassment is a societal problem worldwide. We aimed to assess the frequency, predictive factors, and effects of sexual harassment using a nationwide survey of physicians working in Switzerland. Materials and Methods: We conducted a self-administered questionnaire survey of physicians working in Swiss healthcare institutions. The questionnaire assessed experiences of sexual harassment at work, including frequency, types, and sources of harassment. It also asked about the impact of sexual harassment, whether incidents were reported, and what actions were taken following a report. Results: Among the 1837 physicians that participated in the survey, 575 (31.3%) had experienced sexual harassment at least once during their career. Among those reporting sexual harassment, 39.1% of women and 13.2% of men had experienced harassment at least once in their job. Women reported more verbal harassment, while men reported more physical harassment. Women were also more likely to face both forms combined. The main sources of harassment were colleagues of the same profession (46.7%), patients (42.3%), and superiors (41.0%). The most frequently reported impacts included stress (60.1%), emotional exhaustion (34.7%), reduced motivation at work (30%), and considering leaving the job (7.5%). Gender-men was associated with a lower likelihood of experiencing harassment 0.24 (0.18 to 0.31), whereas working in the German-speaking region was associated with a slightly higher likelihood of having experienced sexual harassment at least once (OR 1.35, 95% CI:1.02-1.81). Conclusions: Sexual harassment is common among physicians in Swiss healthcare institutions. It adversely affects the mental health and career trajectories of both men and women yet remains widely underreported due to fears of reprisals and inaction. Institutions should effectively intervene to ensure that reported incidents result in appropriate actions, and that those who report them receive adequate protection from reprisals.

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Research agenda setting in the mental health of neurodivergent students: A qualitative exploration of students perspectives

Satala, L.; Melashenko, D.; Feeny, A.; Hoxha, D.; Koya, S.; Sanchez-Izquierdo Lozano, C.; Long, Z.; Russell, A.; Murray, A.; Power, L.

2026-07-31 psychiatry and clinical psychology 10.64898/2026.07.29.26359210 medRxiv
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Objectives To identify research priorities for improving the mental health of neurodivergent higher education (HE) students by exploring the perspectives of individuals with lived experience. Design Qualitative study using an online survey. Data was analysed using a deductive-inductive, hybrid semantic thematic analysis. Setting UK higher education institutions. Participants 104 current and former neurodivergent HE students with diverse neurodivergent profiles and intersecting identities. Main outcome measures Participant recommendations regarding priorities for future research on neurodivergent student mental health. Results Six themes were identified and were grouped into (1) general recommendations for research and (2) recommendations specific to neurodivergence within a HE context. Participants prioritised a shift away from medical model approaches towards research informed by social and strengths-based perspectives. Key priorities included improving understanding of diagnostic barriers and misdiagnosis, reducing stigma, investigating institutional barriers within HE, evaluating the effectiveness of support and accommodations and examining the experiences of underrepresented and intersectional groups. Participants emphasised the need for research on more flexible teaching practices, sensory-friendly learning environments, integrated mental health and educational support and alternatives to diagnosis-dependent access to services. Conclusions Future research should move beyond descriptive accounts towards evaluating interventions and current support provision to understand if they improve the mental health of neurodivergent students. Adopting intersectional approaches, moving beyond binary deficit- or strengths-based frameworks and focusing on inclusive, needs-based support rather than diagnosis-led systems are likely to produce more equitable and effective outcomes for neurodivergent students in higher education.